- Title
- Effect of activated charcoal on citalopram-induced QT prolongation: reply (letter)
- Creator
- Isbister, Geoffrey K.; Stokes, Barrie; Buckle, Nicholas A.; Duffull, Stephen B.
- Relation
- Annals of Emergency Medicine Vol. 52, Issue 1, p. 87-88
- Publisher Link
- http://dx.doi.org/10.1016/j.annemergmed.2007.11.046
- Publisher
- American College of Emergency Physicians
- Resource Type
- journal article
- Date
- 2008
- Description
- We thank Greene et al for their comments on our study of citalopram overdoses. They raise a number of issues about the study that we can clarify. We agree that it is difficult to determine how useful QT prolongation is as a predictor of citalopram-induced cardiotoxicity. However, Torsades de Pointes (TdP) has been reported in citalopram overdose and there is a well-known association between QT prolongation and malignant arrhythmias. We have recently shown that the QT nomogram used in our study is a valid approach to assessing an abnormal QT interval and risk of Torsades de Pointes.
- Subject
- citalopram overdoses; charcoal; clinical toxicology; treatments
- Identifier
- uon:5173
- Identifier
- http://hdl.handle.net/1959.13/43039
- Identifier
- ISSN:0196-0644
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